1.

論文(リポジトリ)

論文(リポジトリ)
米須, 清貴 ; Komesu, Seiki ; 山城, 彰子 ; Yamashiro, Akiko ; 山内, 優希 ; Yamauchi, Yuki ; 山口, 剛史 ; Yamaguchi, Takeshi
出版情報: 琉球大学教職センター紀要.  pp.121-132,  2022-03-31.  琉球大学教職センター
2.

論文(リポジトリ)

論文(リポジトリ)
山城, 彰子 ; Yamashiro, Akiko
出版情報: 留学生教育 : 琉球大学留学生センター紀要.  7  pp.77-89,  2010-03.  琉球大学留学生センター
URL: http://hdl.handle.net/20.500.12000/17611
概要: 紀要論文
3.

論文(リポジトリ)

論文(リポジトリ)
Nakasone, Hiroki ; Sgkuawa, Hiroshi ; Nakayoshi, Tmofumi ; Kawakami, Yuko ; Kinjo, Fukunori ; Saito, Atushi ; Yamashiro, Akiko ; Nakayoshi, Tmokuni ; Ikema, Minoru ; Hirayama, Yoshikatsu
出版情報: 琉球医学会誌 = Ryukyu Medical Journal.  16  pp.117-121,  1996.  琉球医学会 — Ryukyu Medical Association
URL: http://hdl.handle.net/20.500.12000/0002016002
概要: The present study examined the efficacy and the predicting factors of response to interferon (IFN) alpha in patients wit h liver cirrhosis associated with hepatitis type C virus infection (LC type C). Sixty-seven patients were treated with IFN alpha and were classified into 2 Groups. Group 1 : Patients with liver cirrhosis, showing histological liver cirrhosis or chronic active hepatitis with lobular disorganization. Group 2 : Patients with chronic hepatitis, showing histological chronic persistent hepatitis or chronic active hepatitis without lobular disorganization. Sustained response to IFN was obtained in 5/17 (29.4%) and 24/50 (48%) of patients in Group 1 and Group 2, respectively. However, the difference was not significant. All patients in Group 2 showed a significant decrease in alanine aminotransferase (ALT) levels during the treatment, whereas 5 of the 17 patients in Group 1 showed no response. All sustained responders in Group 1 who were tested for serum HCV-RNA titer showed low serum HCV-RNA titer, which was less than 10^7 copies/ml, while all except one patient of the non-responders of Group 1 showed above 10^8 copies/ml. It is said that patients with LC type C are more resistant to IFN treatment compared to those with chronic hepatitis type C. However, our findings suggest that even in patients with LC type C, low serum HCV-RNA levels might be associated with better response to IFN.
論文
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