1.

論文(リポジトリ)

論文(リポジトリ)
Nakamura, Hideta ; Ouchi, Gen ; Miyagi, Kazuya ; Higure, Yuuri ; Otsuki, Mariko ; Nishiyama, Naoya ; Kinjo, Takeshi ; Nakamatsu, Masashi ; Tateyama, Masao ; Kukita, Ichiro ; Fujita, Jiro
出版情報: The American Journal of Tropical Medicine and Hygene.  104  pp.1018-1021,  2021-01-13.  The American Society of Tropical Medicine and Hygiene
URL: http://hdl.handle.net/20.500.12000/0002019618
概要: Anticoagulation plays a major role in reducing the risk of systematic thrombosis in patients with severe COVID-19. Serious hemorrhagic complications, such as intracranial hemorrhage, have also been recognized. However, intra-abdominal hemorrhage is under-recognized because of its rare occurrence, despite high mortality. Here, we discuss two cases of spontaneous iliopsoas hematoma (IPH) likely caused by anticoagulants during the clinical course of COVID-19. We also explored published case reports to identify clinical characteristics of IPH in COVID-19 patients. The use of anticoagulants may increase the risk of lethal IPH among COVID-19 patients becsuse of scarce data on optimal dosage and adequate monitoring of anticoagulant effects. Rapid diagnosis and timely intervention are crucial to ensure good patient outcomes. 続きを見る
2.

論文(リポジトリ)

論文(リポジトリ)
Nakamura, Hideta ; Miyagi, Kazuya ; Otsuki, Mariko ; Higure, Yuuri ; Nishiyama, Naoya ; Kinjo, Takeshi ; Nakamatsu, Masashi ; Haranaga, Shusaku ; Tateyama, Masao ; Fujita, Jiro
出版情報: Internal Medicine.  59  pp.2945-2949,  2020-11-15.  The Japanese Society of Internal Medicine — 一般社団法人 日本内科学会
URL: http://hdl.handle.net/20.500.12000/47366
概要: Treatment with tocilizumab (TCZ) to block interleukin-6 (IL-6) signalling is predicted to mitigate cytokine release synd rome (CRS) caused by coronavirus disease 2019 (COVID-19). However, the adverse effects of TCZ on patients with COVID-19 remain unclear. We herein report a patient with COVID-19 treated with TCZ who developed acute hypertriglyceridaemia. Despite favipiravir treatment, acute respiratory distress syndrome developed in a 45-year-old patient with COVID-19; thus, TCZ was initiated. The triglyceride levels greatly increased after TCZ administration. Physicians should consider the negative impact of TCZ on the lipid profile in patients with COVID-19, although COVID-19-induced CRS itself may be an aggravating factor.
論文
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3.

論文(リポジトリ)

論文(リポジトリ)
Nakamura, Hideta ; Tateyama, Masao ; Tasato, Daisuke ; Haranaga, Shusaku ; Higa, Futoshi ; Matsuzaki, Akiko ; Yoshimi, Naoki ; Fujita, Jiro
出版情報: Clinical Case Reports.  8  pp.3439-3443,  2020-10-27.  John Wiley & Sons Ltd.
URL: http://hdl.handle.net/20.500.12000/0002019620
概要: Asymptomatic pulmonary sarcoidosis can develop after starting antiretroviral therapy. The decision on whether to treat sarcoidosis with corticosteroids should be based on the disease severity.
4.

論文(リポジトリ)

論文(リポジトリ)
Nakamura, Hideta ; Kinjo, Takeshi ; Arakaki, Wakako ; Miyagi, Kazuya ; Tateyama, Masao ; Fujita, Jiro
出版情報: Critical Care.  24  2020-08-04.  Critical Care Canada Forum
URL: http://hdl.handle.net/20.500.12000/47368
概要: 論文
5.

論文(リポジトリ)

論文(リポジトリ)
Nakamura, Hideta ; Kinjo, Takeshi ; Arakaki, Wakako ; Miyagi, Kazuya ; Tateyama, Masao ; Fujita, Jiro
出版情報: Critical Care.  24  2020-08-04.  BioMed Central Ltd
URL: http://hdl.handle.net/20.500.12000/0002019622
6.

論文(リポジトリ)

論文(リポジトリ)
Kami-Onaga, Kaoru ; Tateyama, Masao ; Kinjo, Takeshi ; Parrott, Gretchen ; Tominaga, Daisuke ; Takahashi-Nakazato, Ai ; Nakamura, Hideta ; Tasato, Daisuke ; Miyagi, Kyoko ; Maeda, Saori ; Arae, Hirotaka ; Uehara, Hitoshi ; Miyagi, Kazuya ; Haranaga, Shusaku ; Fujita, Jiro
出版情報: PLOS ONE.  13  2018-06-14.  Public Library of Science
URL: http://hdl.handle.net/20.500.12000/45641
概要: In this study, we demonstrated the pervasiveness of HIV-associated neurocognitive disorders (HAND) among a selection of Japanese patients as well as evaluated and comparedthe Mini Mental State Examination (MMSE) and the International HIV Dementia Scale(IHDS) for use as a screening tool among combination anti-retroviral therapy (cART)-naïveand cART experienced patients. The MMSE and the IHDS have both been used as HANDscreening tests around the world with variable success. It has been reported the increasedusage of cART the utility of these screening tests may have been diminished due to thedecreased severity of impairment and the altered pattern of neurocognitive impairments incART era HAND patients. It is therefore possible the MMSE and the IHDS may still be usefulamong cART-naïve patients even in the cART era. However, only one study has investigated and compared the screening results of the IHDS among cART-naïve and cART experienced patients. All HIV positive patients who visited, or were admitted, to the RyukyuUniversity Hospital between January 2009 and March 2014 were evaluated for inclusion.Selected patients (n = 49) had data without omission for all tests. The overall prevalence ofHAND in our cohort was 44%. The area under the curve (AUC), for all subjects using theMMSE and the IHDS, were 0.60 and 0.69, respectively. However, the AUC among cARTnaïve patients were 0.58 and 0.76 for the MMSE and the IHDS, respectively. Whereas,cART experienced patients had an AUC of 0.60 and 0.61, respectively. Overall, the MMSEdemonstrated a poor screening ability for HAND, regardless of cART usage (the cut-offvalue of 27 had a Youden’s J-Index of 0.1, in all groups). Alternatively, the IHDS was moderately useful for HAND screening among cART-naïve patients (the cut-off value of 11 had aYouden’s J-Index of 0.4), but performed poorly as a screening test among cART experienced patients (the cut-off value of 11 had a Youden’s J-Index of 0.1).
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7.

論文(リポジトリ)

論文(リポジトリ)
Tamaki, Yuichiro ; Higa, Futoshi ; Tasato, Daisuke ; Nakamura, Hideta ; Uechi, Kayoko ; Tamayose, Maki ; Haranaga, Shusaku ; Yara, Satomi ; Tateyama, Masao ; Fujita, Jiro
出版情報: Internal Medicine.  50  pp.351-354,  2011.  The Japanese Society of Internal Medicine — 一般社団法人 日本内科学会
URL: http://hdl.handle.net/20.500.12000/47447
概要: Acute lung injury during pregnancy results in morbidity and mortality in both the mother and the fetus. Pneumocystis jir ovecii pneumonia (PCP) is a rare disease but may occur in pregnant immune-suppressed women. Here, we describe a case of acute lung injury due to PCP and alveolar hemorrhage in a pregnant woman who was a human T lymphotropic virus type-1 (HTLV-1) carrier. PCP should be considered in the differential diagnosis of pulmonary complications during pregnancy in HTLV-1 endemic areas.
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